Acute necrotizing tubulointerstitial nephritis due to systemic adenoviral infection

To date, all the reported cases of acute necrotizing tubulointerstitial nep hritis (TIN) secondary to systemic adenovirus infection have occurred in in dividuals with primary or secondary immunodeficiency, and have resulted in renal failure and death. We present the case of a 12-year-old, immunologica lly competent girl who developed acute necrotizing TIN with acute renal fai lure (ARF), hepatitis and meningoencephalitis secondary to a systemic adeno viral infection who completely recovered with supportive care.