Surgical treatment of hypothalamic hamartoma and refractory seizures - A case report and review of the literature

Refractory gelastic seizures are often associated with hypothalamic hamarto ma (HH). Presurgical evaluation in such children often points to a distinct cortical region as the source of the seizures. A case of a child with HH a nd refractory seizures is presented. Video-EEG monitoring revealed a well-d efined epileptic focus in the left frontal region. In accordance with the c urrent understanding of the nature of hamartoma-related seizures, the hamar toma was resected. Follow-up evaluations revealed a marked improvement in s eizure frequency and global functioning. Copyright (C) 2001 S.Karger AG, Ba sel.