Background: Idiopathic sustained ventricular tachycardia originating from t
he left ventricle (ILVT) has been an indication for catheter ablation. The
present study evaluated the clinical features, long-term prognosis and indi
cations for treatment in pediatric patients with ILVT.
Methods: The subjects of the present study were eight patients (four males
and four females) with a mean age at onset of 11.0 years (range 3-15 years)
. The mean follow-up period was 7.7 years (range 2.1-11.3 years).
Results: In electrophysiologic studies, intravenously administered verapami
l was effective for the termination of tachycardia in all six patients who
received this treatment and for the prevention of tachycardia in four of fi
ve patients. Oral administration of verapamil was effective in five of seve
n patients. Propranolol or flecainide was added to the treatment protocol f
or two patients who did not respond to verapamil alone. Tachycardia disappe
ared without drugs in four patients during the follow-up period and became
non-sustained in another patient. Two of three patients with persistent tac
hycardia underwent catheter ablation. Pharmacologic treatment was very effe
ctive for ILVT among these patients.
Conclusions: Pharmacologic therapy, such as with verapamil, is still the tr
eatment of choice for ILVT because of a good long-term prognosis and potent
ial risks and complications by manipulation of catheter ablation.