Several methods are available for assessing drug effects on airway inflamma
tion and the antiinflammatory effects of drugs for asthma. Cromolyn and the
ophylline are well-established drugs for the treatment of asthma, and each
has antiinflammatory properties. Drugs in development include those aimed a
t inhibiting inflammatory mediators and immunoglobulin E function; clinical
studies, however, have been conducted largely in patients with moderate to
severe asthma.