This paper develops an account of explanation in biology which does not inv
olve appeal to laws of nature, at least as traditionally conceived. Explana
tory generalizations in biology must satisfy a requirement that I call inva
riance, but need not satisfy most of the other standard criteria for lawful
ness. Once this point is recognized, there is little motivation for regardi
ng such generalizations as laws of nature. Some of the differences between
invariance and the related notions of stability and resiliency, due respect
ively to Sandra Mitchell and Brian Skyrms, are explored.