Activities of superoxide dismutase and catalase in erythrocytes and plasmatransaminases of goldfish (Carassius auratus gibelio Bloch.) exposed to cadmium
Rv. Zikic et al., Activities of superoxide dismutase and catalase in erythrocytes and plasmatransaminases of goldfish (Carassius auratus gibelio Bloch.) exposed to cadmium, PHYSL RES, 50(1), 2001, pp. 105-111
Four groups of goldfish were exposed to cadmium in a concentration of 20 mg
Cd/l water under aquarium conditions. The duration of exposure was 1, 4, 7
and 15 days. It was shown that the activity of superoxide dismutase (SOD)
in the red blood cells (RBC) significantly decreased after the first day of
cadmium exposure. However, the SOD activity increased after 7 and 15 days
of cadmium treatment. Elevated activity of catalase (CAT) was found in eryt
hrocytes of cadmium-treated fishes after 15 days, whereas plasma GOT levels
was increased after 7 and 15 days and GPT levels after 1, 4, 7 and 15 days
of cadmium treatment. This was accompanied by a significant decrease of bl
ood hemoglobin concentrations (after 15 days) and hematocrit values (after
7 and 15 days). However, the concentration of blood glucose significantly i
ncreased after 1, 4, 7 and 15 days of cadmium exposure. These results indic
ate that cadmium causes oxidative stress and tissue damage in the exposed f
ishes.