Radiation oncology: Contributions of the United States in the last years of the 20th century

The advancements in radiation oncology in the past 50 years in the United S tates were probably more dramatic than those in the first half of the 20th century. Not only were there major technical achievements, but there was al so an associated increase in the overall cure rates of cancer, from 20% at 5 years 50 years ago to now nearly 60% at 5 years. The cure rates in select ed tumor sites at 5 years in 1950 and in 2000, respectively, were as follow s: breast, 50% and 80%; colon and rectum, 40% and 85%; lung, 5% and 15%-20% ; prostate, 40% and 80%; Hodgkin disease, 50% and more than 90%; cervix, 40 % and 70%-80%; uterus (endometrium), 80% and more than 90%; bladder, 30% an d 50%; head and neck, 30% and 60%; and esophagus, 2% and 15%. Much of this has been due to a broader array of techniques in radiation therapy availabl e for treatment but also because of new emphasis on combined integrated mod alitities (surgery, radiation therapy, and chemotherapy). New imaging techn iques have contributed substantially, allowing better selection of patients for treatment and better selections of treatment modalities.