There are different causes leading to formation of pulmonary bullae, in par
ticular tuberculosis. There is some debate concerning the pathophysiology o
f bullae extension although two mechanisms are put forward: partial obstruc
tion of the airways and elastic recoil of adjacent lung parenchyma with a n
egative pressure in the bullae.
Pulmonary function tests are highly perturbed in patients with giant bullae
. The natural hhistory of bullae is enlargement although spontaneous regres
sion is rarely described. Bullae should be resected in selected patients, o
thers require careful follow-up. We present the case of a man with tubercul
osis who developed a giant pulmonary bulla that regressed spontaneousy in a
few years.