2,15-dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor

Authors
Reetz, MT Sostmann, S
Citation
Mt. Reetz et S. Sostmann, 2,15-dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor, TETRAHEDRON, 57(13), 2001, pp. 2515-2520
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
13
Year of publication
2001
Pages
2515 - 2520
Database
ISI
SICI code
0040-4020(20010326)57:13<2515:2(SAUA>2.0.ZU;2-O
Abstract
The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluo rescence sensor for chiral amines and amino alcohols. The fluorescence of H ELIXOL can be efficiently as well as enantioselectively quenched by the ena ntiomers of several chiral amines and amino alcohols. Its high fluorescence intensity and its ability to enantiodiscriminate effectively makes it pote ntially useful for high-throughput screening of ee. (C) 2001 Elsevier Scien ce Ltd. All rights reserved.