D. Sawada et Y. Ito, A new method for formacetal linkage formation: protection of alcohols, phenols and carboxylic acids, TETRAHEDR L, 42(13), 2001, pp. 2501-2504
A new formacetal linkage (ROCH2OR ') forming reaction was developed, which
exploited a combination of sulfide (R ' OCH2SR ") and CuBr2-Bu4NBr. This re
action proceeded to give high yields under neutral conditions and was appli
ed to the protection of alcohols, phenols and carboxylic acids by several t
ypes of alpha -oxymethyl groups. (C) 2001 Elsevier Science Ltd. All rights
reserved.