Development of glaucoma in the course of interferon alpha therapy for chronic hepatitis B

Previous reported ocular complications of interferon alfa administration ar e extremely rare. These include oculomotor palsy, corneal allograft rejecti on, retinal hemorrhage and cotton wool patches. A 15-year-old boy with chro nic hepatitis B was treated with interferon alpha for six months, and then developed glaucoma. After the interferon therapy had been discontinued the glaucoma improved. Accordingly, we report a case of glaucoma development du ring the course of interferon alpha therapy for chronic hepatitis B.