MEDIUM-TERM RESULTS OF DIRECT BRONCHIAL ARTERIAL REVASCULARIZATION USING IMA FOR SINGLE-LUNG TRANSPLANTATION (SLT WITH DIRECT REVASCULARIZATION)

Objective: To describe a technique of direct revascularisation of the bronchial artery using the loft IMA and assess its medium term results in patients undergoing left single lung transplant (SLT). Methods: Be tween March 1991 and September 1993, 22 patients who underwent direct bronchial revascularisation at the time of left SLT (20 pedicled IMA, one free IMA, and one direct anastomosis to the aorta) have been follo wed up for a minimum period of 1 year (mean 30 +/- 12 months). Their m ean age was 47.8 +/- 9.6 and the original disease was emphysema in 19, lymphangioleiomyomatosis in two, and pulmonary fibrosis in one. The m ean ischaemia time was 269.7 +/- 23.4 min. Results: There was one earl y death (4.5%) and 3 patients were re-explored for bleeding. The actua rial survival at 1 and 3 years was 91 +/- 0.4% and 82.6 +/- 1%, respec tively. Bronchial healing was excellent in all patients and angiograph ic studies showed patent vascular anastomosis in all 22 patients, with good nln off in 20 and poor in two. One patient developed clinical ob literative bronchiolitis at 22 months (4.5%) during a period of follow up varying from 12 to 43 months (mean 30 S.D. 12). At last follow up the mean FEVI was 1.4 +/- 0.4 and the mean FVC was 2.2 +/- 0.6. On ave rage, each patient developed 1.5 +/- 0.6 infection episodes and 1 +/- 0.2 acute lung rejection. Conclusion: It is concluded that the medium term results of direct bronchial revascularisation are good. However t he influence of this procedure on long term results needs further inve stigation. (C) 1997 Elsevier Science B.V.