Mm. Filippova et al., BIOLOGICALLY-ACTIVE PEPTIDES, PRODUCTS OF IN-VITRO PROTEOLYSIS OF FUNCTIONAL PROTEINS, Bioorganiceskaa himia, 23(5), 1997, pp. 388-409
Over 100 various peptides were identified as a result of numerous stud
ies of in vitro proteolytic digestion of some proteins and tissue prep
arations. Many of them exhibit wide spectra of biological effects, whi
ch are similar to those described for some groups of endogenous peptid
e bioregulators. The possibility of in vitro modeling of endogenous pr
ocesses of proteolytic digestion of proteins that provides biologicall
y active peptides is discussed.