STRUCTURAL FEATURES OF 4 LONG TERMINAL RE PEATS OF HUMAN ENDOGENOUS RETROVIRUSES AND THEIR INTEGRATION SITES

Authors
KHIL PP KOSTINA MB AZHIKINA TL KOLESNIK TB LEBEDEV YB SVERDLOV ED
Citation
Pp. Khil et al., STRUCTURAL FEATURES OF 4 LONG TERMINAL RE PEATS OF HUMAN ENDOGENOUS RETROVIRUSES AND THEIR INTEGRATION SITES, Bioorganiceskaa himia, 23(5), 1997, pp. 434-440
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
23
Issue
5
Year of publication
1997
Pages
434 - 440
Database
ISI
SICI code
0132-3423(1997)23:5<434:SFO4LT>2.0.ZU;2-L
Abstract
Four LTR-containing regions of human chromosome 19 were sequenced by t he primer walking technique using strings of short oligonucleotides ti ghtly bound to the template. A comparative and evolutionary analysis o f sequences homologous to human endogenous retroviruses (HERV) was per formed, and the prototypes of the LTRs were determined. Analysis of th e chromosome 19 sequences adjacent to LTR revealed that LTRs of KERV-K share a common location with other retroposons.