Vaginal adenosis with adenocarcinoma in situ in a woman with no recognisedantecedent factors

We present a case of vaginal adenosis with adenocarcinoma in situ in a woma n with no recognised antecedent factors. This case demonstrates the importa nce of continuing thorough colposcopic assessment of the entire lower genit al tract with repeated biopsies of all abnormal epithelium in women with pe rsistent or recurrent cervical cytology abnormalities. Successful managemen t requires accurate definition of the vaginal lesion.