Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids

Authors
Wittman, MD Kadow, JF Vyas, DM Lee, FL Rose, WC Long, BH Fairchild, C Johnston, K
Citation
Md. Wittman et al., Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids, BIOORG MED, 11(6), 2001, pp. 811-814
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
6
Year of publication
2001
Pages
811 - 814
Database
ISI
SICI code
0960-894X(20010326)11:6<811:SAAAON>2.0.ZU;2-3
Abstract
The syntheses and antitumor activity of three paclitaxel-chlorambucil hybri ds are presented. Hybrid 3 showed significant in vivo efficacy. (C) 2001 El sevier Science Ltd. All rights reserved.