PERTUSSIS IN THE NETHERLANDS - AN OUTBREAK DESPITE HIGH-LEVELS OF IMMUNIZATION WITH WHOLE-CELL VACCINE

Authors
DEMELKER HE CONYNVANSPAENDONCK MAE RUMKE H VANWIJNGAARDEN JK MOOI FR SCHELLEKENS JFP
Citation
He. Demelker et al., PERTUSSIS IN THE NETHERLANDS - AN OUTBREAK DESPITE HIGH-LEVELS OF IMMUNIZATION WITH WHOLE-CELL VACCINE, EMERGING INFECTIOUS DISEASES, 3(2), 1997, pp. 175-178
Citations number
11
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
EMERGING INFECTIOUS DISEASES → ACNP
Volume
3
Issue
2
Year of publication
1997
Pages
175 - 178
Database
ISI
SICI code
Abstract
In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Althoug h not all potential surveillance artifacts could be excluded, it is hi ghly probable that the data reflect a true outbreak. However, the caus e of this increase has not yet been determined. Further research is di rected to the severity of disease and a possible mismatch between the vaccine and the circulating Bordetella strains.