A survey of rabies postexposure prophylaxis administered by local heal
th departments for a 1-year period showed that very few patients recei
ved treatment as a result of exposure to a confirmed rabid animal. Mos
t prophylaxis was administered for contact with domestic animals in si
tuations where existing recommendations for quarantine or laboratory t
esting of the animal were not followed. Because rabies in domestic ani
mals in Kentucky is uncommon, these findings suggest that had the exis
ting recommendations been followed, the prophylaxis would have been un
necessary in most cases.