Non-specific interstitial pneumonia is characterized pathologically by unif
orm interstitial inflammation and fibrosis. This disease is most commonly d
emonstrated on high resolution CT as subpleural ground-glass opacity mixed
with irregular linear opacities. The authors report a case of non-specific
interstitial pneumonia with high resolution findings consistent with a "cra
zy paving pattern". This appearance, represented by smoothly thickened inte
rlobular septa with a background of geographic areas of ground-glass opacit
y, is unusual for non-specific interstitial pneumonia and was indistinguish
able from other interstitial or alveolar lung diseases.