Background Subfoveal choroidal neovascularization has usually a poor v
isual prognosis. Submacular surgery has been advocated as an alternati
ve treatment. Visual results of this recent surgical technique is unde
r current clinical evaluation. Methods We retrospectively reviewed the
charts of 16 eyes from 15 patients who underwent submacular surgery t
hrough a small retinotomy. Mean follow-up was 8 months (range from 5 t
o 88 weeks): group 1: submacular hemorrhages caused by age-related mac
ular degeneration, 8 eyes; group 2: advanced subfoveal choroidal neova
scularization in age-related macular degeneration, 3 eyes; group 3: yo
ung onset subfoveal choroidal neovascularization, 5 eyes. Results Grou
p 1: mean preoperative visual acuity was 0,024. Postoperative visual a
cuity increased for 5 eyes (63%) and decreased for 3 eyes (37%) (mean
follow-up: 33 weeks). Two eyes had recurrent neovascularization. Group
2: mean preoperative visual acuity was 0.083. Postoperative visual ac
uity decreased for both eyes (mean follow-up: 58 weeks). Two eyes had
recurrent neovascularization. Group 3: mean preoperative visual acuity
was 0,082. Postoperative visual acuity increased for both eyes (mean
follow-up: 26 weeks). Two eyes had recurrent neovascularization. In bo
th groups, recurrent neovascularization was managed by laser photocoag
ulation. Conclusions Surgery of subfoveal choroidal neovascular membra
nes may stabilize or improve visual acuity in young patients. In subfo
veal choroidal neovascularization due to age-related macular degenerat
ion, this technique does not provide currently measurable visual impro
vement excepted in cases complicated by submacular hemorrhage. Results
of future trials comparing surgery with spontaneous evolution or lase
r photocoagulation are necessary.