Oxaliplatin is a new platinum derivative that has significant activity in p
atients with metastatic colorectal carcinoma. Some of these patients may ha
ve been previously treated with radiotherapy. The interaction of radiothera
py with oxaliplatin needs to be further studied. We report a patient with a
dvanced colonic carcinoma who was treated with concomitant chemoirradiation
with oxaliplatin and developed a peculiar dermatitis in the irradiated fie
ld after being exposed to subsequent chemotherapy with oxaliplatin.