We describe the case of a 38-year-old epileptic man with tufted hair follic
ulitis. The condition started 5 years ago after a scalp laceration that had
been sustained 3 months earlier during an epileptic crisis. There then app
eared a circumscribed inflammatory bulging lesion (with exudation and crust
s) that evolved to scarring alopecia with tufts of 20 to 30 apparently norm
al hair shafts. Results of bacteriologic examination of pus extruding from
the dilated follicular ostia revealed Staphylococcus aureus. The cutaneous
pathologic examination showed polymorphous inflammatory exudate in the uppe
r and mid dermis, which was mostly perifollicular, and the presence of norm
al and independent follicles in the deep dermis, which, while ascending. co
nverged to a common dilated follicular channel. The patient was treated suc
cessively with oral flucloxacillin, erythromycin, ciprofloxacin, and amoxic
illin/clavulanic acid and with topical application of erythromycin, clindam
ycin, povidone iodine, and ketoconazole. Transient improvement was followed
by recurrence and enlargement of the affected area.