Nonendemic pemphigus foliaceus presenting as fatal bullous exfoliative erythroderma

Pemphigus foliaceus is a cutaneous autoimmune blistering disease that is ch aracterized by tower morbidity and mortality than those observed in pemphig us vulgaris or paraneoplastic pemphigus. However, erythrodermic forms of th e endemic variant of pemphigus foliaceus have been associated with a higher mortality. We report a case of nonendemic pemphigus foliaceus that present ed as fatal bullous exfoliative erythroderma, and thus. we will emphasize t he inclusion of this entity in the differential diagnosis and the use of sk in direct immunofluorescence in the evaluation of patients with erythroderm a.