Ocular ferning during the menstrual cycle in healthy women

PURPOSE. The aim of the study is to investigate whether tear ferning patter ns change during different phases of the menstrual cycle. METHODS. The tear ferning test was performed on twelve normal women of chil dbearing age at three day intervals throughout one complete menstrual cycle . Serum hormone levels (progesterone, estrogen, testosterone) were measured . RESULTS. Eight women showed type I ferning, and the other four had type II ferning initially. These patterns did not change during the menstrual cycle . Serum hormone levels were all in the normal range. Since no change in fer ning pattern was detected during the menstrual cycle, the ferning test can be done at any time in women. CONCLUSIONS. This study showed no effect of different menstrual cycle phase s on tear ferning patterns.