Microspheres or ethylcellulose have been prepared by the solvent evaporatio
n process, The influence of the agitation rate, the viscosity of the dispel
sed phase, the molecular weight of the polymer and the volume ratio betwee
n the dispersed phase and the continuous one on the drug release rate has b
een studied. The obtained results have been analysed thanks to an experimen
t schedule. (C) 2001 Elsevier Science Ltd. All rights reserved.