Analysis of lymphocyte diversity in the elderly: heteroduplex analysis andalternative techniques

Authors
Cook, JE Beverley, PCL
Citation
Je. Cook et Pcl. Beverley, Analysis of lymphocyte diversity in the elderly: heteroduplex analysis andalternative techniques, EXP GERONT, 36(3), 2001, pp. 583-589
Citations number
32
Categorie Soggetti
Medical Research General Topics
Journal title
EXPERIMENTAL GERONTOLOGY
ISSN journal
05315565 → ACNP
Volume
36
Issue
3
Year of publication
2001
Pages
583 - 589
Database
ISI
SICI code
0531-5565(200103)36:3<583:AOLDIT>2.0.ZU;2-N
Abstract
Heteroduplex analysis allows global analysis of T cell receptor clonality. This review outlines the method, compares it to other available techniques for the study of clonality and reviews current literature on how these are being used to investigate alterations in the T cell repertoire within elder ly individuals. (C) 2001 Elsevier Science Inc. All rights reserved.