A comparison of IgG and IgG1 activity in an early milk concentrate from non-immunised cows and a milk from hyperimmunised animals

Authors
McConnell, MA Buchan, G Borissenko, MV Brooks, HJL
Citation
Ma. Mcconnell et al., A comparison of IgG and IgG1 activity in an early milk concentrate from non-immunised cows and a milk from hyperimmunised animals, FOOD RES IN, 34(2-3), 2001, pp. 255-261
Citations number
23
Categorie Soggetti
Food Science/Nutrition
Journal title
FOOD RESEARCH INTERNATIONAL
ISSN journal
09639969 → ACNP
Volume
34
Issue
2-3
Year of publication
2001
Pages
255 - 261
Database
ISI
SICI code
0963-9969(2001)34:2-3<255:ACOIAI>2.0.ZU;2-Q
Abstract
This paper reports on the activity of bovine immunoglobulins IgG and IgG1 d irected towards 19 microbial pathogens in an early milk concentrate from no n-immunised cows and in a hyperimmune milk using an ELISA technique. Both p roducts contained IgG and IgG1 which bound to all the microbial antigens te sted. The early milk concentrate demonstrated a significantly higher Ige an d IgG1 antibody titre (P < 0.05) against all of the antigens tested than th e hyperimmune milk. In addition, the early milk concentrate was shown to st imulate the accumulation of immune cells in the peritoneum of Balb/c mice. <(c)> 2001 Elsevier Science Ltd. All rights reserved.