Burkitt's acute lymphocytic leukemia (L(3)ALL) in adults

Authors
Fenaux, P Bourhis, JH Ribrag, V
Citation
P. Fenaux et al., Burkitt's acute lymphocytic leukemia (L(3)ALL) in adults, HEMAT ONCOL, 15(1), 2001, pp. 37
Citations number
42
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
ISSN journal
08898588 → ACNP
Volume
15
Issue
1
Year of publication
2001
Database
ISI
SICI code
0889-8588(200102)15:1<37:BALL(I>2.0.ZU;2-4
Abstract
The prognosis for Burkitt's acute lymphocytic leukemia (L(3)ALL) in childre n and adults had long been regarded as uniformly poor because of frequent c entral nervous system (CNS) involvement and early relapses. During the last 15 years, however, the survival rate has improved in children, with the us e of aggressive protocols combining intensive induction and consolidation c hemotherapy and early treatment of CNS disease. The impact of these new app roaches on the outcome of adult L(3)ALL has also been subsequently demonstr ated.