Radical surgery of colon cancers directly invading the duodenum, pancreas and liver

Background/Aims: Adjacent organ invasion is observed in 5-12% of the colore ctal cancers and is rarely faced with invasion of the duodenum, pancreas or liver. Methodology: We reviewed 4 patients with invasion of the duodenum, pancreas or liver or more than one at the same time, to emphasize the importance of aggressive radical procedures. Results: Three patients underwent en bloc pancreaticoduodenectomy with righ t hemicolectomy, and one patient underwent en bloc pancreaticoduodenectomy with right hemicolectomy and 5th and 6th hepatic segments resection. Periop erative need for blood transfusion was 3-5 units. There was no postoperativ e morbidity and mortality, except for the patient who had a bile leakage wh ich got well with medical treatment. Although malignant invasion was proved by pathologic evaluation, only one patient had lymph node involvement. Whi le one patient was lost at the 8th postoperative month, 3 patients are livi ng disease free within a range of 14-41 months. Conclusions: The chances of longer survival can be given to the patient by en bloc radical resections of locally advanced right colon tumors accompani ed by invasion of duodenum, pancreas and liver, with low morbidity and mort ality rates.