Chemical reactivity of desferrioxamine mesylate modulated by micellar solutions

The nature of the rate accelerating and retarding effects of cationic, anio nic, zwitterionic and non-ionic micelles on the proton catalysed hydrolysis of desferrioxamine mesylate (desferal), a trihydroxamic acid, has been stu died by kinetic methods using visible spectroscopy. Characteristic features of the media and of the desferal in the reactivity behaviour are discussed . The binding constants of desferal (by hydrophobic or electrostatic effect s) to the micelle are seen to be related to the nature of micellar Surface.