Synthesis, characterization and in-vitro antitumour studies on some 3d-metal complexes of N-salicyloyl-N '-thiobenzhydrazide

Authors
Singh, NK Srivastava, A Kayastha, AM
Citation
Nk. Singh et al., Synthesis, characterization and in-vitro antitumour studies on some 3d-metal complexes of N-salicyloyl-N '-thiobenzhydrazide, I J CHEM A, 39(10), 2000, pp. 1074-1078
Citations number
13
Categorie Soggetti
Chemistry
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY
ISSN journal
03764710 → ACNP
Volume
39
Issue
10
Year of publication
2000
Pages
1074 - 1078
Database
ISI
SICI code
0376-4710(200010)39:10<1074:SCAIAS>2.0.ZU;2-V
Abstract
A few complexes [Mn(SBth)(H2O)(2)], (Me4N)[Pd(HSBth)Cl-2]. [M(HSBth)(SBth)] [M(III)=Fe or Mn] and [M(SBth)(acac)] [M(III)=Co or Cr)] have been prepare d from a potential tetradentate ligand, N-salicyloyl-N'-thiobenzhydrazide ( H(2)SBth). The complexes have been characterized by elemental analyses, mag netic susceptibility measurements, UV-Vis, IR and NMR studies. H(2)SBth and its complexes have shown remarkable in vitro antitumour activity against P -815 (murine mastocytoma) tumour cells.