Invasive pulmonary aspergillosis with thrombosis in the left atrium

We report a female patient with left atrial wall invasion from pulmonary as pergillosis. She had been treated for diabetes mellitus. Pulmonary aspergil losis extended to the left atrial wall via the left pulmonary vein and form ed a polypoid lesion in the left atrium. The polypoid lesion was composed o f thrombus, and the thrombus increased in size to become large, and it show ed invagination into the mitral valve during diastole. We considered that t he thrombus was formed on the injured endocardium. Severe invasive aspergil losis thus could occur in a mild systemic immunocompromised host.