Cerebral atrophy and convulsive seizures after recovery from cerebral edema and coma in a patient with fulminant hepatitis B

We report a 48-year-old woman who developed convulsive seizures and cerebra l atrophy after recovery from fulminant hepatitis B with coma and cerebral edema at the acute stage. Neurological disturbances and cerebral signs are rare sequelae of fulminant hepatic failure (FHF); only a few cases have rep orted in the literature. Cortical laminar necrosis secondary to cerebral ed ema or delayed neuronal death due to toxic substances may have caused delay ed brain atrophy and epileptogenesis.