Recurrent cerebral embolism in a familial amyloid polyneuropathy patient who received partial liver transplantation from a living donor

Cerebral embolism in relation to cardiac amyloidosis has not been widely no ted.A 47-year-old woman who had been suffering from familial amyloid polyne uropathy (FAP) for 7 years was treated with partial liver transplantation f rom a living donor and her early postoperative course was uneventful. Durin g the 391st to 613th postoperative day she experienced recurrent cerebral i nfarctions, but clinical examinations revealed no disorders capable of prod ucing cerebral embolism. At autopsy splenic infarction and intracardiac thr ombi adhering to the mitral valve and left atrium were found, and these are as showed severe amyloid deposition. Amyloid heart is considered to be one possible cause of systemic embolism.