Anxiety is common in the ''pink puffer'' syndrome associated with chro
nic obstructive pulmonary disease (COPD). The degree of anxiety correl
ates well with perceived dyspnoea. This pilot study examines the effec
t of group psychotherapy on anxiety, exercise tolerance, dyspnoea and
quality of life. Ten patients with moderately severe, stable COPD (mea
n forced expiratory volume in one second (FEV1)=1.15 L) had six 90 min
sessions of cognitive and behavioural psychotherapy at weekly interva
ls. Patients completed the Hospital Anxiety and Depression Scale (HADS
), Medical Research Council Questionnaire (MRCQ) and St George's Respi
ratory Questionnaires (SGRQ), 1 week before and after therapy. FEV1, f
orced vital capacity (FVC), slow vital capacity (SVC), blood gas tensi
ons and 6 min walking distance (6MWD) were measured. Eight control pat
ients attended weekly for lung function and 6MWD for 6 weeks, but had
no psychotherapy. Mean baseline HADS score was significantly higher in
the psychotherapy group (12) than in controls (7), but otherwise ther
e were no differences in lung function, blood gas tensions, 6MWD, or t
he other questionnaire scores between groups. After treatment, the phy
siological and psychological parameters where unchanged in both groups
with the exception of the mean 6MWD, which had improved in the psycho
therapy group only, from 351 to 423 m (p<0.001), an increase of 24%. T
hree months after treatment, the 6MWD was still 16% above the baseline
value (p=0.02). In conclusion, six sessions of cognitive and behaviou
ral psychotherapy produced a sustained improvement in exercise toleran
ce in a group of 10 anxious patients with severe chronic obstructive p
ulmonary disease, without any change in anxiety scores on the Hospital
Anxiety and Depression Scale. Further studies of more prolonged, inte
nsive psychotherapy would establish whether better symptom and quality
of life scores accompany more dramatic increases in exercise toleranc
e in ''pink puffers''.