REACTION OF BETA-CYCLODEXTRIN WITH N-2,3-EPOXYPROPYLPHTHALIMIDE - PREPARATION, CHARACTERIZATION AND STUDY OF A NEW SUBSTITUTED CYCLOHEPTAAMYLOSE - EFFECTS ON THE WATER SOLUBILITY OF DRUGS

Authors
DELGADO R VIRGILI A GARCIAANTON JM PARENTE A
Citation
R. Delgado et al., REACTION OF BETA-CYCLODEXTRIN WITH N-2,3-EPOXYPROPYLPHTHALIMIDE - PREPARATION, CHARACTERIZATION AND STUDY OF A NEW SUBSTITUTED CYCLOHEPTAAMYLOSE - EFFECTS ON THE WATER SOLUBILITY OF DRUGS, Journal of inclusion phenomena and molecular recognition in chemistry, 28(3), 1997, pp. 205-212
Citations number
13
Categorie Soggetti
Chemistry,Crystallography
Journal title
Journal of inclusion phenomena and molecular recognition in chemistry → ACNP
ISSN journal
09230750
Volume
28
Issue
3
Year of publication
1997
Pages
205 - 212
Database
ISI
SICI code
0923-0750(1997)28:3<205:ROBWN->2.0.ZU;2-U
Abstract
The reaction of beta-cyclodextrin with N-2,3-epoxypropylphthalimide yi elded a set of new amorphous host compounds with high solubility which was transmitted to the corresponding host-guest complexes. The struct ure was determined by comparing the H-1- and C-13-NMR spectra with tho se of the parent compound, the degree of substitution by integration o f the corresponding NMR signals, and C, H, and N elemental analysis.