Experimental studies of capsular equator rings of soft latex

Purpose: To determine the efficacy of wide equatorial rings of various mate rials in reducing posterior capsule opacification (PCO) and maintaining the circular contour of the capsular equator in a rabbit model. Setting: Laboratory for Intraocular Microsurgery and Implants, Goldschleger Eye Research Institute, Tel-Aviv University, Sheba Medical Center, Tel-Has homer, Israel. Methods: Closed rings made of poly(methyl methacrylate), Teflon(R), polyure thane, and latex were introduced into the capsular bags of rabbit eyes afte r removal of the lens material. The soft latex rings were deemed the only p ractical rings for atraumatic implantation through a small incision. Latex rings of 2 dimensions with rectangular edges were implanted in 8 rabbits. O ne eye served as a control after lens removal and no ring implantation. The eyes were followed for up to 5 months and then evaluated by light microsco py, Results: Posterior capsule opacification was minimal or absent in all anima ls implanted with the latex rings. Mild to moderate inflammatory reaction w as noted in most eyes. it was caused by the ring material or secondary to l ong-standing pressure on the ciliary tissue. The rings also maintained well the circular contour of the capsular bags. Conclusions: Equatorial rings of soft latex with sharp rectangular edges we re effective in minimizing PCO and maintaining the shape of the capsule aft er lens removal in rabbits. Soft rings made of a biocompatible material may be effective in humans. (C) 2001 ASCRS and ESCRS.