Three conservative approaches to treatment of interstitial pregnancy

Interstitial pregnancy is among the most dangerous types of ectopic pregnan cy. Four such pregnancies in three women were treated by three conservative modalities with favorable results. A 10-week interstitial pregnancy was su ccessfully treated by laparoscopic-guided local methotrexate (MTX) injectio n into the gestational sac. Six years later the same woman had a repeat unr uptured interstitial pregnancy at 9 weeks' gestation, with the gestational sac located in the same location as the previous one. Laparoscopic cornuost omy was performed. An asymptomatic woman in the eighth week of an interstit ial pregnancy was treated with systemic MTX, but despite decreasing beta -h uman chorionic gonadotropin levels, cornual rupture occurred. The patient w as successfully treated by laparoscopic cornuostomy. The final patient was admitted in hypovolemic shock and hemoperitoneum and was treated successful ly for ruptured 8-week interstitial pregnancy by laparoscopic cornuostomy.