Synthesis and biological evaluation of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones

Authors
Khunt, R Datta, N Bharmal, F Parikh, AR
Citation
R. Khunt et al., Synthesis and biological evaluation of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones, J INDIAN CH, 78(1), 2001, pp. 47-48
Citations number
5
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
ISSN journal
00194522 → ACNP
Volume
78
Issue
1
Year of publication
2001
Pages
47 - 48
Database
ISI
SICI code
0019-4522(200101)78:1<47:SABEO3>2.0.ZU;2-4
Abstract
3-Aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones (3a-m, 4a-m) h ave been synthesised by the condensation of thioglycolic acid/thiolactic ac id with N-aryl-(2-chloro-7-methoxyquinolin-3-yl)azomethine (2a-m) which in turn are prepared from arylamine and 2-chloro-7-methoxyquinoline-3-carboxal dehyde (1). The products have been evaluated for their antibacterial and an tifungal activities.