A. Salerno et M. Georgesco, Short latency facilitation between pairs of threshold magnetic stimuli studied in amyotrophic lateral sclerosis, NEUROP CLIN, 31(1), 2001, pp. 48-52
The aim of the present study was to investigate the effects of short latenc
y facilitation between pairs of threshold magnetic stimuli on the motor cor
tex of amyotrophic lateral sclerosis (ALS) patients, at an interstimulus in
terval (ISI) of 1-5 ms. As compared to controls, the facilitatory effects n
ormally recorded at ISI 1 and 3 ms were considerably reduced. This suggeste
d that the neuronal circuitry responsable for these effects, which is suppo
sed to be the same as those generating I-waves, is impaired in ALS. (C) 200
1 Editions scientifiques et medicales Elsevier SAS.