We describe a patient with an incidental adrenal myelolipoma associate
d with biochemical evidence of Cushing's syndrome who lacked the physi
cal stigmata of cortisol excess (subclinical Gushing's syndrome). Path
ologic examination revealed the presence of adrenocortical cells mixed
with myelolipomatous tissue. Although cases of clinically evident Gus
hing's syndrome due to adrenal myelolipomas have been reported previou
sly, to our knowledge this is the first report associating adrenal mye
lolipoma and subclinical Gushing's syndrome.