Several aromatic lipophilic compounds belong to Polyaclic Aromatic Hydrocar
bons (PAHs). They show similar physico-chemical and toxicological propertie
s. Dioxins (polychorobibenzoparadioxin/furan or PCDD/F) are the most well-k
nown among these compounds, then PCBs (polychlorobiphenyls) and non chlorin
ated PAHs (made of 2 to 6 aromatic cycles). Those compounds are released by
anthropic activities and most environmental matrixes are contaminated(soil
, water, air). According to their lipophilic properties, they are linked wi
th hydrophobic compartments and may be concentrated in lipids, especially a
t the end of the food chain. Risk assessment and risk management need some
advances in the understanding of the fate of these molecules in biological
matrixes and an improvement of analytical procedure. Transfer of PCB and HA
P throughout the food chain has not been extensively described and there is
a lack of data concerning their bioavailability for human.