Ethyl(methyl)dioxirane as an efficient reagent for the oxidation of nucleoside phosphites into phosphates under nonbasic anhydrous conditions

Authors
Kataoka, M Hattori, A Okino, S Hyodo, M Asano, M Kawai, R Hayakawa, Y
Citation
M. Kataoka et al., Ethyl(methyl)dioxirane as an efficient reagent for the oxidation of nucleoside phosphites into phosphates under nonbasic anhydrous conditions, ORG LETT, 3(6), 2001, pp. 815-818
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
6
Year of publication
2001
Pages
815 - 818
Database
ISI
SICI code
1523-7060(20010322)3:6<815:EAAERF>2.0.ZU;2-B
Abstract
[GRAPHICS] A convenient method for the oxidation of nucleoside phosphites into phospha tes under nonbasic and nonaqueous conditions using commercially available e thyl(methyl)dioxirane has been developed. This oxidation is effective with both N-protected and N-unprotected strategies.