Effect of protease inhibitors combined with standard antiretroviral therapy on linear growth and weight gain in human immunodeficiency virus type 1-infected children

Authors
Dreimane, D Nielsen, K Deveikis, A Bryson, YJ Geffner, ME
Citation
D. Dreimane et al., Effect of protease inhibitors combined with standard antiretroviral therapy on linear growth and weight gain in human immunodeficiency virus type 1-infected children, PEDIAT INF, 20(3), 2001, pp. 315-316
Citations number
10
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
PEDIATRIC INFECTIOUS DISEASE JOURNAL
ISSN journal
08913668 → ACNP
Volume
20
Issue
3
Year of publication
2001
Pages
315 - 316
Database
ISI
SICI code
0891-3668(200103)20:3<315:EOPICW>2.0.ZU;2-E
Abstract
Children with HIV-1 infection and poor growth have a significant increase i n the risk of death. We studied the effects of protease inhibitors on the h eight and weight of 27 HIV-1-infected children and found that in our small pilot study, protease inhibitor therapy had a positive effect on the height s of HIV-1-infected children. Accelerated height velocity was sustained for at least 18 to 20 months.