S. Poller et L. Hesse, ACUTE GLAUCOMA IN AGE-RELATED MACULAR DEG ENERATION DUE TO SUBRETINALHEMORRHAGE AND DISORDER OF PLATELET-FUNCTION, Klinische Monatsblatter fur Augenheilkunde, 210(6), 1997, pp. 384-387
Background Hemorrhages from subretinal neovascularisations in age-rela
ted macular degeneration are not uncommon, but usually limited to the
posterior pole. A therapy-resistant angle closure glaucoma following d
isplacement of the lens-iris diaphragm due to massive choroidal and su
bretinal hemorrhages has rarely been reported. Case report A 72-year-o
ld female patient was first seen in september 1993 because of decrease
d vision in the right eye. An age related macular degeneration with an
extended untreatable neovascularisation membrane was diagnosed. One y
ear later sudden pain attacks were initiated by secondary angle closur
e glaucoma, caused by a massive choroidal and subretinal bleeding. At
first the IOP could be regulated by drug therapy, however, recurring h
emorrhages led to continuously elevated IOP. The reason for the recurr
ent massive hemorrhages was found to be a disorder of the platelet fun
ction. Since the IOP (50-80 mmHg) could not be controlled any further,
we decided to perform a sclerotomy in an attempt to drain the blood.
Within one day another bleeding occurred and again led to an increase
in IOP. Finally, the patient agreed to have the eye enucleated. Conclu
sion In case of massive hemorrhages in age related macular degeneratio
n a haematological systemic disorder must be included in the diagnosti
c considerations. If the intraocular pressure can not be lowered neith
er medically nor surgically, enucleation can not be avoided.