Despite widespread immunization against Bordetella pertussis, whooping coug
h remains potentially fatal in susceptible populations such as neonates, A
case of neonatal pertussis with severe pulmonary hypertension (PH) requirin
g extracorporal membrane oxygenation (ECMO) is described, PH associated wit
h pertussis severe enough to require ECMO is frequently irreversible and as
sociated with a poor prognosis.