Background The idiopathic polypoidal choroidal vasculopathy, also know
n as ''posterior uveal bleeding syndrome'' or ''multiple recurrent ser
osanguineous retinal pigment epithelial detachments in black women'' i
s a rare disease entity. A clincopathologic correlation of a patient w
ith this disease is presented. Case report A 47-year-old black woman w
as evaluated for a decrease of visual acuity in her right eye which ha
d occurred over the last 3 months. Ophthalmic examination of her right
eye revealed sub-RPE hemorrhage associated with a reddish-orange subr
etinal vascular-like lesion. In addition, both eyes displayed a few ch
oroidal vascular-like bulbous structures in the superior temporal peri
papillary region. The patient developed an extensive choroidal hemorrh
age that led eventually to the enucleation of the eye. Conclusion Chor
oidal neovascular membranes (CNV) secondary to idiopathic polypoidal c
horoidal vasculopathy differs in many aspects from other entities asso
ciated with CNV including clinical and fluorescein angiographic featur
es, clinical course, and prognosis.