We examine the behavior of an anisotropic brane-world in the presence of in
flationary scalar fields. We show that. contrary to naive expectations, a l
arge anisotropy does not adversely affect inflation. On the contrary, a lar
ge initial anisotropy introduces more damping into the scaler field equatio
n of motion, resulting in greater inflation. The rapid decay of anisotropy
in the brane-world significantly increases the class of initial conditions
from which the observed universe could have originated. This generalizes a
similar result in general relativity. A unique feature of Bianchi type I br
ane-world cosmology appears to be that for scalar fields with a large kinet
ic term the initial expansion of the Universe is quasi-isotropic. The Unive
rse grows more anisotropic during an intermediate transient regime until an
isotropy finally disappears during inflationary expansion.