PURPOSE: To investigate the use of activated charcoal to mark the biopsy si
te and needle track after large-core-needle breast biopsy.
MATERIALS AND METHODS: Three hundred seventy-six consecutive patients (with
383 lesions) were referred for stereotactic breast biopsy. Two hundred for
ty seven lesions were carbon marked when the need for surgery was likely. P
atients who underwent marking were followed up for the results of surgery o
r mammography performed at our institution. Specimen sizes obtained by usin
g the carbon mark were compared with sizes of consecutive biopsy specimens
obtained after hook-wire localization.
RESULTS: Carbon marking was well tolerated in all cases. All 132 surgeries
performed at the authors' institution were successful in removing the marke
d target. Specimen sizes compared favorably with sizes of comparison hook-w
ire localization specimens. All 68 lesions followed mammographically reveal
ed no changes that were attributable to the use of carbon. Two minor compli
cations were observed. Two small cancers were completely removed at needle
biopsy.
CONCLUSION: Carbon marking is safe and effective for marking the biopsy sit
e and needle track created by stereotactic large-core-needle biopsy of the
breast. Marking eliminates the need for postprocedural needle localization.
It remains effective when small lesions have been completely removed. This
technique should be considered in properly selected cases by those perform
ing large-core-needle biopsy of the breast.