Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: Pilot results in the breast

Authors
Pogue, BW Poplack, SP McBride, TO Wells, WA Osterman, KS Osterberg, UL Paulsen, KD
Citation
Bw. Pogue et al., Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: Pilot results in the breast, RADIOLOGY, 218(1), 2001, pp. 261-266
Citations number
16
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
RADIOLOGY
ISSN journal
00338419 → ACNP
Volume
218
Issue
1
Year of publication
2001
Pages
261 - 266
Database
ISI
SICI code
0033-8419(200101)218:1<261:QHTWDN>2.0.ZU;2-D
Abstract
The authors describe what is, to the best of their knowledge, the first qua ntitative hemoglobin concentration images of the female breast that were fo rmed with model-based re-construction of near-infrared intensity-modulated tomographic datal The results in 11 patients, including two with breast tum ors with pathologic correlation, are summarized. Hemoglobin concentration a ppears to correlate with tumor vascularity without the need for exogenous c ontrast material and thereby has intrinsic diagnostic value.